il-1 alpha — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T24816	SP-100030	SP100030,SP 100030	NF-κB
	SP-100030 is a dual inhibitor of NF-κB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both. It effectively reduces the production of IL-2, IL-8, and TNF-alpha in Jurkat and ...
T77080	Manfidokimab
	Manfidokimab (AK120), an IgG4 monoclonal antibody targeting the interleukin 4 receptor alpha (IL-4Rα), demonstrates therapeutic efficacy as detailed in reference [1].
T80854	Vopikitug
	Vopikitug, a human IgG1-kappa monoclonal antibody targeting the IL2RA (interleukin 2 receptor alpha subunit, IL-2RA, TAC, p55, CD25), exhibits antineoplastic activity [1].

Cat No.	Product Name	Synonyms	Targets
T4S0795	Berberrubine chloride	9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline	IL Receptor
	1. Berberrubine chloride (9-Berberoline Chloride) has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expressio...
T5S1981	alpha-Cyperone	(+)-α-Cyperone,α-Cyperone	Others , Endogenous Metabolite
	1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced...

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01738	IL-1 alpha/IL-1A Protein, Mouse, Recombinant	Mouse	E. coli
	IL-1 alpha/IL-1A Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is P01582.
TMPY-00854	IL-1 alpha/IL-1A Protein, Human, Recombinant	Human	HEK293 Cells
	IL-1 alpha/IL-1A Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18 kDa and the accession number is P01583.
TMPJ-00162	IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 54 KDa and the accession number is P01583.
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPK-00920	IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and b...
TMPK-00474	IL-22RA1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	IL-22 receptor, also known as IL-22 R alpha 1 and CRF2-9, is an approximately 65 kDa transmembrane glycoprotein in the type II cytokine receptor family (CRF).Component of the receptor for IL20, IL22 and IL24. Component o...
TMPJ-00161	IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated	Human	E. coli
	IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated is expressed in E. coli expression system with C-Avi tag. The predicted molecular weight is 19 KDa and the accession number is P01583.
TMPY-05836	IL-1 alpha/IL-1A Protein, Rat, Recombinant	Rat	E. coli
	IL-1 alpha/IL-1A Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.80 kDa and the accession number is P16598.
TMPY-01047	IL-1R1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-1R1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63 kDa and the accession number is P14778.
TMPY-01258	IL-13RA1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-00856	TCCR Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	TCCR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 79 kDa and the accession number is Q6UWB1.
TMPY-01170	IL-13RA1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IL-13RA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is O09030.
TMPY-01871	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)	Human	HEK293 Cells
	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
TMPY-01250	IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.2 kDa and the accession number is Q64385.
TMPY-02879	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158)	Human	E. coli
	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158) is expressed in E. coli expression system. The predicted molecular weight is 17.2 kDa and the accession number is Q9UHA7.
TMPY-00437	IL-11R alpha chain 1/IL-11RA1 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	IL-11R alpha chain 1/IL-11RA1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.1 kDa and the accession number is A6IIX5.
TMPY-06520	IL-4R alpha & IL-13R alpha 1 Heterodimer Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-4R alpha & IL-13R alpha 1 Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.52 kDa and the accession number is NP_000409.1.
TMPK-00289	IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low af...
TMPK-00317	IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPK-00512	IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)	Cynomolgus	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPK-01105	IL-22RA1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), ...
TMPK-00356	IL-27RA/TCCR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-27Ra (also known as TCCR and WSX1) as a gene whose expression can induce the transformation of hematopoietic cells. IL-27Ra (IL-27R) is a type I cytokine receptor that functions as the ligand binding component of the ...
TMPK-00316	IL-18R alpha Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPJ-00291	IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to...
TMPK-01071	IL-22RA1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), ...
TMPJ-01424	IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His)	Macaca Mulatta	HEK293 Cells
	Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is prod...
TMPY-01048	IL-1R1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-1R1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is P14778.
TMPY-03426	IL-1R1 Protein, Human, Recombinant	Human	HEK293 Cells
	IL-1R1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.8 kDa and the accession number is P14778.
TMPK-00537	IL-10R alpha/IL-10RA Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	IL-10R alpha/IL-10RA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25.34 kDa and the accession number is A0A2K5WJ66.
TMPK-00334	IL-10R alpha/IL-10RA Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	IL-10R alpha/IL-10RA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession number is Q13651.
TMPK-00335	IL-10R alpha/IL-10RA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	IL-10R alpha/IL-10RA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession number is Q13651.
TMPK-00272	IL-13RA1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha,...
TMPY-06579	IL-13RA1 Protein, Human, Recombinant(aa 1-343, His & Avi), Biotinylated	Human	HEK293 Cells
	IL-13RA1 Protein, Human, Recombinant(aa 1-343, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 40.15 kDa and the accession number is NP_001551.1.
TMPY-06590	IL-13RA1 Protein, Human, Recombinant (aa 1-343, hFc)	Human	HEK293 Cells
	IL-13RA1 Protein, Human, Recombinant (aa 1-343, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.62 kDa and the accession number is NP_001551.1.
TMPK-00273	IL-13Ra1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha,...
TMPY-05543	TCCR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	TCCR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.6 kDa and the accession number is AAC40121.1.
TMPY-06792	TCCR Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	TCCR Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 56.37 kDa and the accession number is AAC40121.1.
TMPY-01074	IL-13RA1 Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	IL-13RA1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 65 kDa and the accession number is P78552-1.
TMPY-05123	IL-13RA1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	IL-13RA1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-00454	IL-28B Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IL-28B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.1 kDa and the accession number is Q8CGK6.
TMPJ-00119	IL-22RA2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. I...
TMPY-05795	IL-13RA1 Protein, Mouse, Recombinant (mFc)	Mouse	HEK293 Cells
	IL-13RA1 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 62.41 kDa and the accession number is O09030.
TMPY-05432	IL-13RA1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	IL-13RA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.8 kDa and the accession number is O09030.
TMPH-02438	IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO)	Rhesus	E. coli
	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammat...
TMPY-01956	IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant	Mouse	E. coli
	IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is Q9JLA2-1.
TMPJ-00270	IL-13RA1 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	Interleukin-13 receptor subunit alpha-1(IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TR...
TMPY-02818	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His)	Human	E. coli
	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 19.2 kDa and the accession number is Q9UHA7.
TMPY-00076	IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.5 kDa and the accession number is P26952-1.
TMPY-00592	IL-3R alpha/CD123 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IL-3R alpha/CD123 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.9 kDa and the accession number is EDL20630.1.
TMPJ-00981	PTX3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory...
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